Goat Anti-TLR2 Polyclonal IgG Antibody?

This AffiAB® Goat Anti-TLR2 Polyclonal IgG Antibody has been research-validated for use in Western blotting.

What is Goat Anti-TLR2 Polyclonal IgG Antibody ?

The Goat Anti-TLR2 Polyclonal IgG Antibody is an antibody specifically designed to target and bind to Toll-like receptor 2 (TLR2). TLR2 is a type of pattern recognition receptor (PRR) that plays a crucial role in the recognition and initiation of immune responses against a wide range of pathogens, including bacteria, fungi, and viruses.

How are they generated ?

Polyclonal antibodies are generated by immunizing animals, in this case, goats, with a specific antigen—in this case, TLR2. The immune system of the goat recognizes TLR2 as foreign and mounts an immune response, producing a diverse population of antibodies that target different epitopes on TLR2. After the immunization, the serum containing the polyclonal antibodies is collected from the goat and used for various applications.

Where is it useful ? 

Goat Anti-TLR2 Polyclonal IgG Antibody is particularly useful in research settings for detecting and quantifying TLR2 protein levels in various biological samples. It can be used in techniques such as immunoblotting (Western blot), immunohistochemistry (IHC), immunofluorescence (IF), and enzyme-linked immunosorbent assays (ELISA). The polyclonal nature of the antibody allows for binding to multiple epitopes on the TLR2 protein, enhancing its sensitivity and specificity in detecting TLR2.

It's important to note that antibodies are highly specific to their target antigens, and the Goat Anti-TLR2 Polyclonal IgG Antibody will bind specifically to TLR2 proteins. This specificity allows researchers to study the expression, localization, and function of TLR2 in various tissues, cell types, and experimental conditions.

When using this antibody, it's crucial to follow the manufacturer's instructions regarding the recommended dilutions, storage conditions, and appropriate controls to ensure accurate and reliable results. Additionally, it's recommended to include proper positive and negative controls in experiments to validate the specificity of the antibody and rule out any non-specific binding.